For 45 years Sal worked at Carlo's Bakery in Hoboken, where he worked originally under "Cake Boss" star Buddy Valastro’s father.
In 2009 Picinich stopped appearing on "Cake Boss" when he started battling cancer.
"The minute he didn't go down to Carlo's Bakery was the minute I knew Sal was starting to feel pain," his wife said.
He briefly returned to "Cake Boss" last year for the Employee of the Century of the Award, which he accepted on the 100th anniversary of the bakery.
We send our condolences to all at Carlo's Bakery and to the Picinich family.
